Review



a20 tnfaip3  (Cell Signaling Technology Inc)


Bioz Verified Symbol Cell Signaling Technology Inc is a verified supplier
Bioz Manufacturer Symbol Cell Signaling Technology Inc manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
    • 92
      Buy from Supplier

    Structured Review

    Cell Signaling Technology Inc a20 tnfaip3
    Minnelide suppresses TGFβ-induced upregulation of signaling pathways. ( A-C ) Protein expression of HSP70/72, <t>A20,</t> Vimentin, MYC and BRD4 was shown in human MDA-MB-231 and murine 4T1 and EMT6 cell lines treated with increased dose of Minnelide in the presence and absence of recombinant human TGFβ. Experiments were done in duplicates. ( D) TCGA data showing the genetic alterations of myc in Basal-like, ER- and ER + breast cancer subtypes. ( E–G) Kaplan–Meier TCGA data showing the association between the Myc expression levels and survival rates among the patients with high gene expression (red) in Basal-like, ER- and ER + breast cancer compared to patients with low expression (blue), respectively.
    A20 Tnfaip3, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 92/100, based on 3 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/a20 tnfaip3/product/Cell Signaling Technology Inc
    Average 92 stars, based on 3 article reviews
    a20 tnfaip3 - by Bioz Stars, 2026-06
    92/100 stars

    Images

    1) Product Images from "Dual activity of Minnelide chemosensitize basal/triple negative breast cancer stem cells and reprograms immunosuppressive tumor microenvironment"

    Article Title: Dual activity of Minnelide chemosensitize basal/triple negative breast cancer stem cells and reprograms immunosuppressive tumor microenvironment

    Journal: Scientific Reports

    doi: 10.1038/s41598-024-72989-6

    Minnelide suppresses TGFβ-induced upregulation of signaling pathways. ( A-C ) Protein expression of HSP70/72, A20, Vimentin, MYC and BRD4 was shown in human MDA-MB-231 and murine 4T1 and EMT6 cell lines treated with increased dose of Minnelide in the presence and absence of recombinant human TGFβ. Experiments were done in duplicates. ( D) TCGA data showing the genetic alterations of myc in Basal-like, ER- and ER + breast cancer subtypes. ( E–G) Kaplan–Meier TCGA data showing the association between the Myc expression levels and survival rates among the patients with high gene expression (red) in Basal-like, ER- and ER + breast cancer compared to patients with low expression (blue), respectively.
    Figure Legend Snippet: Minnelide suppresses TGFβ-induced upregulation of signaling pathways. ( A-C ) Protein expression of HSP70/72, A20, Vimentin, MYC and BRD4 was shown in human MDA-MB-231 and murine 4T1 and EMT6 cell lines treated with increased dose of Minnelide in the presence and absence of recombinant human TGFβ. Experiments were done in duplicates. ( D) TCGA data showing the genetic alterations of myc in Basal-like, ER- and ER + breast cancer subtypes. ( E–G) Kaplan–Meier TCGA data showing the association between the Myc expression levels and survival rates among the patients with high gene expression (red) in Basal-like, ER- and ER + breast cancer compared to patients with low expression (blue), respectively.

    Techniques Used: Expressing, Recombinant



    Similar Products

    a20 tnfaip3  (Cell Signaling Technology Inc)
    92
    Cell Signaling Technology Inc a20 tnfaip3
    Minnelide suppresses TGFβ-induced upregulation of signaling pathways. ( A-C ) Protein expression of HSP70/72, <t>A20,</t> Vimentin, MYC and BRD4 was shown in human MDA-MB-231 and murine 4T1 and EMT6 cell lines treated with increased dose of Minnelide in the presence and absence of recombinant human TGFβ. Experiments were done in duplicates. ( D) TCGA data showing the genetic alterations of myc in Basal-like, ER- and ER + breast cancer subtypes. ( E–G) Kaplan–Meier TCGA data showing the association between the Myc expression levels and survival rates among the patients with high gene expression (red) in Basal-like, ER- and ER + breast cancer compared to patients with low expression (blue), respectively.
    A20 Tnfaip3, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/a20 tnfaip3/product/Cell Signaling Technology Inc
    Average 92 stars, based on 1 article reviews
    a20 tnfaip3 - by Bioz Stars, 2026-06
    92/100 stars
    		  Buy from Supplier
    trem2 signaling pathway sampler kit  (Cell Signaling Technology Inc)
    92
    Cell Signaling Technology Inc trem2 signaling pathway sampler kit
    Minnelide suppresses TGFβ-induced upregulation of signaling pathways. ( A-C ) Protein expression of HSP70/72, <t>A20,</t> Vimentin, MYC and BRD4 was shown in human MDA-MB-231 and murine 4T1 and EMT6 cell lines treated with increased dose of Minnelide in the presence and absence of recombinant human TGFβ. Experiments were done in duplicates. ( D) TCGA data showing the genetic alterations of myc in Basal-like, ER- and ER + breast cancer subtypes. ( E–G) Kaplan–Meier TCGA data showing the association between the Myc expression levels and survival rates among the patients with high gene expression (red) in Basal-like, ER- and ER + breast cancer compared to patients with low expression (blue), respectively.
    Trem2 Signaling Pathway Sampler Kit, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/trem2 signaling pathway sampler kit/product/Cell Signaling Technology Inc
    Average 92 stars, based on 1 article reviews
    trem2 signaling pathway sampler kit - by Bioz Stars, 2026-06
    92/100 stars
    		  Buy from Supplier
    anti a20 tnfaip3  (Cell Signaling Technology Inc)
    92
    Cell Signaling Technology Inc anti a20 tnfaip3
    Minnelide suppresses TGFβ-induced upregulation of signaling pathways. ( A-C ) Protein expression of HSP70/72, <t>A20,</t> Vimentin, MYC and BRD4 was shown in human MDA-MB-231 and murine 4T1 and EMT6 cell lines treated with increased dose of Minnelide in the presence and absence of recombinant human TGFβ. Experiments were done in duplicates. ( D) TCGA data showing the genetic alterations of myc in Basal-like, ER- and ER + breast cancer subtypes. ( E–G) Kaplan–Meier TCGA data showing the association between the Myc expression levels and survival rates among the patients with high gene expression (red) in Basal-like, ER- and ER + breast cancer compared to patients with low expression (blue), respectively.
    Anti A20 Tnfaip3, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/anti a20 tnfaip3/product/Cell Signaling Technology Inc
    Average 92 stars, based on 1 article reviews
    anti a20 tnfaip3 - by Bioz Stars, 2026-06
    92/100 stars
    		  Buy from Supplier

    Image Search Results


    Minnelide suppresses TGFβ-induced upregulation of signaling pathways. ( A-C ) Protein expression of HSP70/72, A20, Vimentin, MYC and BRD4 was shown in human MDA-MB-231 and murine 4T1 and EMT6 cell lines treated with increased dose of Minnelide in the presence and absence of recombinant human TGFβ. Experiments were done in duplicates. ( D) TCGA data showing the genetic alterations of myc in Basal-like, ER- and ER + breast cancer subtypes. ( E–G) Kaplan–Meier TCGA data showing the association between the Myc expression levels and survival rates among the patients with high gene expression (red) in Basal-like, ER- and ER + breast cancer compared to patients with low expression (blue), respectively.

    Journal: Scientific Reports

    Article Title: Dual activity of Minnelide chemosensitize basal/triple negative breast cancer stem cells and reprograms immunosuppressive tumor microenvironment

    doi: 10.1038/s41598-024-72989-6

    Figure Lengend Snippet: Minnelide suppresses TGFβ-induced upregulation of signaling pathways. ( A-C ) Protein expression of HSP70/72, A20, Vimentin, MYC and BRD4 was shown in human MDA-MB-231 and murine 4T1 and EMT6 cell lines treated with increased dose of Minnelide in the presence and absence of recombinant human TGFβ. Experiments were done in duplicates. ( D) TCGA data showing the genetic alterations of myc in Basal-like, ER- and ER + breast cancer subtypes. ( E–G) Kaplan–Meier TCGA data showing the association between the Myc expression levels and survival rates among the patients with high gene expression (red) in Basal-like, ER- and ER + breast cancer compared to patients with low expression (blue), respectively.

    Article Snippet: Antibodies against cMyc (ab32072, Abcam), vimentin (5741, Cell Signaling Technology), A20/TNFAIP3 (NBP1-77,533, Novus), HSP70/72 (ADI-SPA-810-F, Enzo Life Sciences), Brd4 (ab128874, Abcam), and ß-actin (664803, BioLegend).

    Techniques: Expressing, Recombinant